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Mini PCs · Head to head

Asus ROG NUC 16 (RTX 5060 32GB + 1TB) vs Asus ROG NUC 16 (RTX 5080 64GB + 2TB)

Full Mini PCs comparison in 2026

Updated October 2026
Data from Amazon and official Asus site.
2026 verdict
Nothing in this chassis is held back in the Asus ROG NUC 16 (RTX 5080 64GB + 2TB), which is the machine to pick over the Asus ROG NUC 16 (RTX 5060 32GB + 1TB).
Asus ROG NUC 16 (RTX 5080 64GB + 2TB)
Winner
Asus ROG NUC 16 (RTX 5080 64GB + 2TB)
$4999.00

Last recorded price

Buy on Amazon USA
The top build doubles the memory to 64 GB and the storage to 2 TB, and moves to an RTX 5080 Laptop GPU with 16 GB of GDDR7 and a 24-core Core Ultra 9 290HX Plus, so it suits large creative workloads and local models rather than gaming alone. The 5060 keeps the same cooling, ports and upgrade paths with a 280W adapter, 32 GB of faster DDR5-6400 and a 1 TB drive, and it is the lighter, cheaper machine. One detail cuts the other way: the 64 GB kit runs at DDR5-5600, below the 6400 the chassis supports. Pick the 5080 build when the workload needs the memory and space now, and the 5060 when a higher graphics tier is the only thing that matters.
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FeatureAsus ROG NUC 16 (RTX 5060 32GB + 1TB)Asus ROG NUC 16 (RTX 5080 64GB + 2TB)Winner
Price$2499.00$4999.00Asus ROG NUC 16 (RTX 5060 32GB + 1TB)
Rating4.44.2Asus ROG NUC 16 (RTX 5060 32GB + 1TB)
Memory Speed6400 MT/s5600 MT/sAsus ROG NUC 16 (RTX 5060 32GB + 1TB)
Memory Capacity32 GB64 GBAsus ROG NUC 16 (RTX 5080 64GB + 2TB)
GPU ModelNVIDIA GeForce RTX 5060 Laptop GPU (8GB GDDR7)NVIDIA GeForce RTX 5080 Laptop GPU (16GB GDDR7)Asus ROG NUC 16 (RTX 5080 64GB + 2TB)
Storage Capacity1 TB2 TBAsus ROG NUC 16 (RTX 5080 64GB + 2TB)
CPU ModelIntel Core Ultra 7 270HX PlusIntel Core Ultra 9 290HX PlusDifferent strengths
NPU ModelNPU Intel AI BoostIntel AI Boost NPU (13 TOPS)Different strengths
Warranty3 years3 yearsTie
Memory ConfigurationDual-channelDual-channelTie
Memory TypeDDR5DDR5Tie

What the differences mean

Graphics and frame buffer

The Asus ROG NUC 16 (RTX 5060 32GB + 1TB) carries an RTX 5060 Laptop GPU with 8 GB of GDDR7, while the Asus ROG NUC 16 (RTX 5080 64GB + 2TB) carries an RTX 5080 with 16 GB. The extra buffer lifts ray tracing and local model work.

Memory capacity

The Asus ROG NUC 16 (RTX 5060 32GB + 1TB) ships 32 GB and the Asus ROG NUC 16 (RTX 5080 64GB + 2TB) ships 64 GB, both upgradable to 128 GB. The larger kit matters for long timelines, virtual machines and big datasets.

Storage

The Asus ROG NUC 16 (RTX 5060 32GB + 1TB) holds a 1 TB drive and the Asus ROG NUC 16 (RTX 5080 64GB + 2TB) a 2 TB drive, both in an M.2 2280 PCIe 4.0 slot that accepts up to 4 TB with PCIe 5.0 support.

Processor

The Asus ROG NUC 16 (RTX 5060 32GB + 1TB) pairs its GPU with a 20-core Core Ultra 7 270HX Plus. The Asus ROG NUC 16 (RTX 5080 64GB + 2TB) runs the 24-core Core Ultra 9 290HX Plus, adding eight efficient cores for heavy CPU work.

Memory speed

The Asus ROG NUC 16 (RTX 5060 32GB + 1TB) uses DDR5-6400 CSO-DIMM modules, the fastest the chassis supports. The factory 64 GB kit in the Asus ROG NUC 16 (RTX 5080 64GB + 2TB) runs at DDR5-5600, a step below the platform's ceiling.

Which one to buy if

Asus

Asus ROG NUC 16 (RTX 5060 32GB + 1TB)

Prime exclusive deal
$2499.00

Last recorded price

Buy on Amazon USA
  • + Price: $2499.00
  • + Rating: 4.4
  • + Memory Speed: 6400 MT/s
  • - Memory Capacity: 32 GB vs 64 GB
  • - GPU Model: NVIDIA GeForce RTX 5060 Laptop GPU (8GB GDDR7) vs NVIDIA GeForce RTX 5080 Laptop GPU (16GB GDDR7)

Upgrading from the Asus ROG NUC 16 (RTX 5060 32GB + 1TB)?

Stepping up from the Asus ROG NUC 16 (RTX 5060 32GB + 1TB) to the Asus ROG NUC 16 (RTX 5080 64GB + 2TB) is the biggest jump in the line: the RTX 5080 brings 16 GB of GDDR7 instead of 8, memory doubles to 64 GB and storage to 2 TB, and the processor moves to the 24-core Core Ultra 9 290HX Plus. The chassis, cooling, five video outputs, seven USB ports and Wi-Fi 7 are unchanged, and both remain upgradeable. One wrinkle: the factory 64 GB kit runs at DDR5-5600, below the DDR5-6400 the smaller build uses. If the 5060 already handles your games, the step is only worth it for GPU rendering, large creative projects or local models.

Price history compared

Every price change of both, in the same store, so the gap between the two lines is what one costs more than the other.

  • Asus ROG NUC 16 (RTX 5060 32GB + 1TB)
  • Asus ROG NUC 16 (RTX 5080 64GB + 2TB)

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Frequently Asked Questions

Which is better overall: Asus ROG NUC 16 (RTX 5060 32GB + 1TB) or Asus ROG NUC 16 (RTX 5080 64GB + 2TB)?

The Asus ROG NUC 16 (RTX 5080 64GB + 2TB) is the most capable machine, with a 16 GB RTX 5080, 64 GB of memory and a 2 TB drive. The Asus ROG NUC 16 (RTX 5060 32GB + 1TB) is the better value if gaming is the main job and you do not need that much memory.

What is the biggest difference between the Asus ROG NUC 16 (RTX 5060 32GB + 1TB) and the Asus ROG NUC 16 (RTX 5080 64GB + 2TB)?

Graphics memory and RAM. The Asus ROG NUC 16 (RTX 5060 32GB + 1TB) has an 8 GB RTX 5060 and 32 GB of DDR5-6400, while the Asus ROG NUC 16 (RTX 5080 64GB + 2TB) has a 16 GB RTX 5080, 64 GB of DDR5-5600 and a 2 TB drive.

Can both be upgraded later?

Yes. The Asus ROG NUC 16 (RTX 5060 32GB + 1TB) and the Asus ROG NUC 16 (RTX 5080 64GB + 2TB) both have tool-free thumb screws, memory that reaches 128 GB and an M.2 2280 slot taking drives up to 4 TB with PCIe 5.0 support.

Do they have the same ports and cooling?

Yes. Both use triple-fan cooling over a dual vapor chamber and offer two HDMI 2.1 FRL, two DisplayPort 2.1, Thunderbolt 4, seven USB ports, a 3.5 mm audio jack, Wi-Fi 7 and 2.5G Ethernet.

Which one has faster memory?

The Asus ROG NUC 16 (RTX 5060 32GB + 1TB), whose modules run at DDR5-6400, the platform's ceiling. The Asus ROG NUC 16 (RTX 5080 64GB + 2TB) ships a 64 GB kit running at DDR5-5600, a step below.

Who should buy each one?

Buy the Asus ROG NUC 16 (RTX 5080 64GB + 2TB) for GPU rendering, large creative projects, local models or a white build. Buy the Asus ROG NUC 16 (RTX 5060 32GB + 1TB) for compact high-refresh gaming where the top graphics tier would go unused.

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